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Pregnant or breastfeeding women are typically advised against use due to the unknown risks

The GBA effects its influence on depression through neuroinflammatory pathways alteration of neurotransmitter precursors and the secondary dysregulation of HPA axis

[DOI] [PMC free article] [PubMed] [Google Scholar] 79.Casciola-Rosen L., Thiemann D.R., Andrade F., Trejo-Zambrano M.I., Leonard E.K., Spangler J.B., Skinner N.E., Bailey J., Yegnasubramanian S., Wang R., et al

However, individuals with absorption issues or severe deficiencies may benefit more from B12 injections due to their rapid and direct delivery of the vitamin into the bloodstream

Andrew Huberman, Ph.D