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Gene-expression changes in dermal fibroblast cultures exposed to GHK-Cu collagen, decorin, and matrix-metalloproteinase regulation

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The combination of GPX4 inhibitors with immune checkpoint inhibitors (ICIs) targeting the PD-1/PD-L1 axis increases the proportion of CD8 + T cells, enhances their cytotoxic activity and induces ferroptosis, thereby promoting chemotherapy resistance [42]

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1 Introduction Cardio-Cerebrovascular Diseases (CCVDs) are the collective terms for cardiovascular and cerebrovascular diseases, which refer to ischemic or hemorrhagic diseases of heart, brain and systemic tissues caused by hyperlipidemia, hyperglycemia and hypertension (Vasan et al., 2001