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Therapeutic strategies targeting FOXO transcription factors

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The cycling rationale relates to receptor sensitivity research: continuous GHSR stimulation may produce receptor desensitization over extended periods in some research models

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Nanoparticle delivery systems, such as lipid nanoparticles, polyion complex micelles, pH-responsive polymer nanoparticles, and biodegradable polymer nanoparticles, facilitate the transport of nucleic acid therapeutics