Both affect inflammatory processes, though through distinct mechanisms
ACS Chem Neurosci 13:486496
3-Methylcholanthrene did not cause significant alterations in epoxide hydrolase immunohistochemical staining, but phenobarbital and trans-stilbene oxide produced significant alterations in the intensity and lobular pattern of distribution (Kawabata et al
Vaduganathan M, Filippatos G, Claggett BL, Desai AS, Jhund PS, Henderson A, Brinker M, Kolkhof P, Schloemer P, Lay-Flurrie J, et al
Metformin may suppress the key ferroptosis driver ACSL4 (which promotes toxic lipid biosynthesis) through AMPK pathway activation or reduce iron-dependent cellular damage by modulating iron metabolism-related proteins (e.g., downregulating transferrin receptor)