The application of Selank offset the decrease
An intravenous formulation of NAC (trade name Acetadote), FDA-approved in 2004, is reserved for patients with altered mental status, gastrointestinal bleeding, history of a caustic ingestion, or refractory emesis despite the use of antiemetics
However, in animal cells, and especially in human erythrocytes, the principal antioxidant enzyme for H 2 O 2 detoxification has for a long time been considered to be GPX, as catalase has much lower affinity for H 2 O 2 than GPX (2,27)
Simpson JP, Di Leo R, Dhanoa PK, Allan WL, Makhmoudova A, Clark SM, Hoover GJ, Mollen RT, Shelp BJ (2008) Identification and characterization of a plastid localized Arabidopsis glyoxylate reductase isoform: comparison with a cytosolic isoform and implications for cellular redox homeostasis and aldehyde detoxification
doi: 10.1053/jhep.2002.34943