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575 Similarly, the loss of mitochondrial complex I leads to a decrease in the ratio of NAD + /NADH and can inhibit the activity of Sirt3, thereby enhancing the protein acetylation and mPTP sensitivity

The mutagenicity of AFB1 following treatment by this enzyme was reduced by about 50%70%, suggesting that the highly reactive and toxic 8,9-epoxide did not accumulate in the reaction

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Antibody responses to citrullinated and noncitrullinated antigens in the sputum of subjects with rheumatoid arthritis and subjects at risk for development of rheumatoid arthritis