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This shift directly impacts microglial behavior, where succinate accumulation triggers inflammatory cascades, highlighting how MRIS propagates injury across cell types [114]

( Epigallocatechin-3-gallate Epigallocatechin-3-gallate (EGCG), a catechin monomer extracted from tea leaves, is the main active component of tea polyphenols and has antioxidant and anti-inflammatory effects ( + Treg

In the second step of biosynthesis, glutathione synthetase (GS) adds the final amino acid, glycine, to complete the glutathione molecule