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The damaging chemicals (free radicals) the body creates as a consequence of metabolism are what the term oxidative stress refers to

Polyene antibiotics, such as amphotericin B, which contains seven conjugated double bonds, are subject to attack by peroxyl radicals, leading to aggregation and loss of activity

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In many cases, protein glutathionylation was observed in an endogenous milieu, but its functional change and physiological impact were not studied