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In patients with T2DM who do not have atherosclerotic cardiovascular disease (ASCVD)/indicators of high-risk, HF, or CKD and who need to minimize hypoglycemia and/or promote weight loss, GLP-1 RAs are generally recommended as a second or third-line option as add-on to metformin therapy

This schedule uses the largest practical dilution (3.0 mL) to keep perinjection units 10 for better accuracy

Methionine kicks fat to the curb, preventing its stash in the liver

Once reconstituted, solutions require immediate refrigeration between 2C to 8C to maintain molecular integrity over subsequent experimental phases

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