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[85] [86] Nicotine dependence involves aspects of both psychological dependence and physical dependence, since discontinuation of extended use has been shown to produce both affective (e.g., anxiety, irritability, craving, anhedonia) and somatic (mild motor dysfunctions such as tremor) withdrawal symptoms

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Nicotine Levels Nicotine, a natural alkaloid found in tobacco plants, is a stimulant that can cause side effects such as headache, dizziness, nausea, and shortness of breath

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