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Its targeted mechanism makes it relevant in studies focused on weight management and metabolic health

doi: 10.1152/ajpendo.00203.2003

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Recent studies have shown that insulin-mediated suppression of hepatic gluconeogenesis occurs indirectly through the ability of insulin to suppress adipocyte lipolysis and the flux into liver pyruvate carboxylase, the rate-limiting enzyme in gluconeogenesis (183, 200)