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During pregnancy, nutritional needs increase to support the growth and development of the fetus and to improve the tissue reserves and metabolic demands of the mother

This range derives from scaling the effective doses in rat studies (approximately 10 micrograms per kilogram of body weight) to human physiology using established interspecies conversion factors

Endocrinol Res Pract

It has been suggested that a discrepancy between the biological and chronological age of the endometrium (i.e., premature aging of the endometrium) in young women may account for some cases of endometrial factor infertility

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