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doi: 10.3389/fphar.2014.00168 Received 11 May 2014 Accepted 25 June 2014 Published 17 July 2014 Volume 5 - 2014 Edited by Alfonso Pompella, Universit di Pisa, Italy Reviewed by Jose A

It attacks the hydrogen atom of an amino acid residue to form a carbon-centered radical that reacts with oxygen to generate an alkyl-peroxyl radical and then in two steps an alkoxyl radical

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1

However, glutathione levels naturally decline with age, environmental stressors, toxin exposure, illness, and high physical or mental demand

10.14411/fp.2001.012 Folia Parasitol