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Some studies have suggested that excluding participants who had gastroenteritis prior to the first use of PPIs or correcting for confounding factors, such as susceptibility and time dependence of bacterial gastrointestinal infections, can remarkably reduce the association between PPI treatment and bacterial gastroenteritis (Garcia Rodrguez and Ruigmez, 1997

It ramps up synthesis of collagen types I and III, along with elastin, fortifying the dermal sheath around each follicle