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In clinical practice, a B1-B6-B12 injection may be considered when oral therapy is insufficient or not feasible, such as in malabsorption, severe deficiency, or when accelerated replenishment is desired under medical supervision

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Breastfeeding Methylcobalamin is distributed into breast milk in amounts similar to those in maternal plasma, and distribution in breast milk allows for adequate intakes of methylcobalamin by breastfeeding infants