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Also, ASNase consumption of Asp and glutamate could be supplemented by SLC1A3, thus eliminating the inhibitory effect of ASNase and promoting tumor development

Nikiforov, C

Sakuma S., Ishimura M., Yuba Y., Itoh Y., Fujimoto Y

The common adverse effects include mild, transient headaches, and skin eruptions ranging from mild to severe drug reactions such as fatal StevensJohnson syndrome and toxic epidermal necrolysis, kidney and liver dysfunction, thyroid dysfunction, severe abdominal pain, and fatal complications such as air embolism or sepsis due to incorrect method of IV administration.[] TOPICAL FORMULATIONS Topical formulations of glutathione are also available in the form of cream, facewash, soap, and lotion

Mukai, S