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For example, IV GSH infusions were shown to significantly prevent nerve damage (neuropathy) associated with the chemotherapy drug cisplatin in patients with advanced gastric cancer Topical and Combination Efficacy: Studies confirm that topical application (for example, a 2 percent lotion) can reduce melanin indices and improve skin texture, particularly in conditions like melasma

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Physiol Chem Phys 10 , 483500 (1978)