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Ancient Greek, Persian, and Roman physicians documented using snow, ice, and cold water for treating injuries and diseases

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Additionally, it decreases inflammation by reducing pro-inflammatory cytokines and increasing anti-inflammatory ones, thereby improving insulin sensitivity and decreasing tissue inflammation [41, 233]

Furthermore, by promoting Nrf2 expression and activating HO-1, it significantly reduces ROS levels and MDA content in the kidneys of AKI rats, increases levels of GSH, GPX4, and other anti-ferroptosis proteins, markedly reduces the number of apoptotic cells in the kidneys and renal tubular epithelial cells of model rats, and promote the expression levels of pro-apoptotic proteins, thereby protecting the kidneys (181)

Your skin may look flushed or feel warm to the touch