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This would mean comparing their impacts on SLE-specific immunological biomarkers such as autoantibodies titers, complement proteins (C3, C4), cytokines such as IL-6, IL-10, and TNF-, and T cell subsets (especially the Th17/Treg ratio), to assess efficacy and monitor disease progression, and clinical manifestations

Starting at 3 months of age, mice received small injections of Deltaran for five days each month until their natural deaths

Toxicol Mech Methods (2017) 27(7):51827

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Providers commonly track IGF-1 and metabolic markers during a protocol and adjust dosing to keep it within an appropriate range