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There are no human trials, so we dont know side effects

Laboratory research may investigate: enzymatic pathways involved in NAD+ synthesis and recycling interactions between NAD-dependent enzymes and metabolic signaling networks cellular responses to altered nicotinamide availability These investigations are typically conducted in controlled in vitro systems and molecular biology research platforms

Genomics 84 , 10141020 (2004)

Phase 2 trial (Lancet 2021) tested cagrilintide 0.3 mg through 4.5 mg/week as monotherapy and reported a clear dose-response, with 10.8% mean weight loss at 4.5 mg/week at 26 weeks

It is likely that all radiation response modifiers affect multiple aspects of biology that are of possible relevance to the outcome