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Pharmaceuticals, 16 (11), Article 1615

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Abbreviations ASDs: Anti-seizure drugs TCM: Traditional Chinese Medicine PWE: Patients with epilepsy KA: Kainic acid JNK: C-Jun N-terminal kinase GAS: Gastrodin VPA: Valproic acid SE: Status epilepticus PTZ: Pentylenetetrazole EEG: Electroencephalogram TLE: Temporal lobe epilepsy mEC: Medial entorhinal cortex Nav 1.6: Voltage-gated sodium channel 1.6 IL-1: Interleukin-1 TNF-: Tumor necrosis factor- IL-10: Interleukin-10 MAPK: Mitogen-activated protein kinases cAMP: Cyclic adenosine monophosphate CREB: CAMP-response element binding protein NF-B: Nuclear factor kappa-B GABA: -Aminobutyric acid RAGE: Receptor for advanced glycation end products TLR: Toll-like receptor BDNF: Brain-derived neurotrophic factor NMDA: N -Methyl-d-aspartic acid MES: Maximum electric shock SSA: Saikosaponin A SREDs: Spontaneous recurrent epileptiform discharges HNC: Hippocampal neuron culture AE: Acquired epilepsy GLAST: Glutamate and aspartate transporter Sal B: Salvianolic acid B PPI: Proteinprotein interaction PTE: Post-traumatic seizures GCK: Ginsenoside compound K GT: Gintonin Nrf2: Nuclear factor erythroid2-related factor 2 NPs: Nanoparticles ICES: Increasing current electroshock seizures MDA: Malondialdehyde MFS: Mossy fiber sprouting CACNA1A: Subunit of P/Q type Ca2+ channel GABRD: Subunit of GABAA receptor DARTS: Drug affinity responsive target stabilization GLP: Ganoderma lucidum polysaccharide CaMKII: Ca2+/calmodulin-dependent protein kinase II 6-GIN: 6-Gingerol OtoN: Otophylloside N TTD: Tetrandrine sEPSCs: Spontaneous excitatory postsynaptic currents mEPSCs: Miniature EPSCs XNJ: Xingnaojing Injection PI3K: Phosphatidylinositol-3-kinase Grp 78: Glucose regulatory protein 78 EA: Electro-acupuncture TRPA1: Transient receptor potential ankyrin 1 5-HT1A: 5-Hydroxytryptamine 1A CMS: Chronic mild stress CUMS: Chronic unpredictable mild stress HJSD: Huazhuo Jiedu Shugan Decoction AC: Adenylate cyclase TLJN: Tongluojiunao POCD: Postoperative cognitive dysfunction RCTs: Randomized control trials References Devinsky O, Hesdorffer DC, Thurman DJ, Lhatoo S, Richerson G

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