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Limitations of Current Evidence The absence of large-scale human clinical trials represents the primary evidence gap

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While the potential impact of boosting your NAD levels with supplements are still being researched, there is a firm understanding that NAD-boosting supplements are a safe way to address age-related decline in NAD that has shown benefit in early studies across various consequences of aging

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Vitamin B12 deficiency is linked to hematologic, neurologic, and psychiatric diseases, plus cardiovascular decline