Ann NY Acad Sci 959 : 133166
When administered intravenously, IONPs have a half-life ranging from 40 minutes to 24 hours and tend to accumulate in macrophages of the liver and spleen
The Journal of Nutrition, 151 (8), 2153
However, most studies assessing safety issues or toxicity of -tocopherol supplementation have lasted only a few weeks to a few months, and side effects associated with long-term -tocopherol supplementation have not been adequately studied
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