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Glutathione in plants: biosynthesis and physiological role in environmental stress tolerance
Anti-inflammatory effects were also reported by the downregulation of neutrophil L-selectin (SELL) and elastase (ELANE), which are associated with neutrophil accumulation and the development of chronic skin wounds ( Estrogen was also shown to play a crucial role in controlling oxidative stress, a major contributor to impaired wound healing, by increasing the production of antioxidants, such as superoxide dismutase (SOD), and promoting B-cell lymphoma 2 (BCL2) expression, via activation of the nuclear factor erythroid 2-related factor (NRF2) (Kanda and Watanabe, 2003
PD patients also exhibit a wide variety of non-motor symptoms, ranging from anosmia, rapid eye movement (REM) sleep disorders, and constipation to severe psychiatric symptoms such as dementia (6)
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