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Cotreatment with TNBS and cigarette smoke exacerbated these effects, leading to increased weight loss, elevated DAI scores, shortened colon length, additional tissue and mucosal damage evident from histopathological analysis, and increased murine endoscopic index of colitis severity (MEICS) (Fig

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The treatment dynamically regulated microbiome diversity and composition, highlighting a potential therapeutic mechanism for COPD through gutlung interactions (Fig

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