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showed that AS-IV activates the cAMP/PKA pathway, increasing phospholamban (PLN) phosphorylation at Ser16 and relieving PLN-mediated inhibition of sarcoplasmic reticulum Ca 2+ ATPase 2a, thereby reducing spontaneous Ca 2+ release in post-I/R mice and lowering the risk of AF (Zhang et al., 2012)

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Pathological correlation Women with both anterior and posterior adenomyosis had shown higher co-existence of ovarian endometriosis and pelvic adhesion, whereas women with only posterior adenomyosis had shown heavy menstrual bleeding and oviduct obstruction