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[oai_citation:4PubMed]( [oai_citation:5PMC]( 4) Growth-hormone receptor (GHR) expression in tendon fibroblasts Gene-expression and protein studies found dose- and time-dependent up-regulation of GHR

It contains 0.9% benzyl alcohol as a preservative, which inhibits bacterial growth after repeated vial access

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Preparation of cigarette smoke extract CSE was prepared according to the previous study (Chen et al., 2009)

1 Remove Epithalon vial from refrigeration and allow to reach room temperature (1520 minutes) 2 Clean vial top with alcohol swab and allow to air dry completely 3 Using a sterile syringe, draw the calculated volume of bacteriostatic water (BAC water) 4 Inject BAC water slowly down the side of the vial do not aim directly at the powder 5 Gently swirl in circular motions DO NOT shake vigorously as this degrades the peptide 6 Allow 23 minutes for full dissolution solution should be clear and colorless 7 Draw calculated dose into an insulin syringe for subcutaneous injection 8 Inject into abdomen, thigh, or upper arm