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Data Availability Statement The data presented in this study are available on request from the corresponding authors.

NAD+ therapy is also being investigated in contexts like healthy aging and neuroprotection, and it has been trialed as an adjunct in addiction recovery programs to reduce withdrawal symptoms, though formal clinical trial data are still sparse

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Tirzepatide for managing overweight and obesity (TA1026)

Phase 2 trial data published in the New England Journal of Medicine (2023) demonstrated significant weight reduction in adults with obesity, and Phase 3 trials are ongoing (ClinicalTrials.gov)