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Biothiols and oxidative stress markers and polymorphisms of TOMM40 and APOC1 genes in Alzheimer's disease patients

Cys 2 ), cystine-free (Cys 2 -free), or cystine-free/GSH-supplemented (750 M) medium for the indicated timepoints, and cell numbers were determined (n = 2 technical replicates representative of one experiment)

For decades, these cells were viewed primarily through the lens of neuroinflammation and neuronal damage, particularly due to their well-documented release of pro-inflammatory cytokines, including TNF-, IL-1, and IL-6 in conditions like AD and PD [124, 453455]

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Melanotan 2 is not a controlled drug under the Misuse of Drugs Act 1971, so it can lawfully be supplied in the UK as a research chemical