The team went above and beyond to ensure I was comfortable and informed every step of the way
Conditions include alcoholic liver disease, viral hepatitis, cirrhosis, and primary or metastatic liver cancer Renal dysfunction : Impaired kidney function reduces B12 elimination, causing accumulation even with normal intake Haematological conditions : Myeloproliferative neoplasms, chronic myeloid leukaemia, polycythaemia vera, and hypereosinophilic syndrome increase transcobalamin production, elevating total serum B12 Laboratory interference : Macro-B12 (immunoglobulin-bound B12) and assay interference can cause spuriously elevated results without true excess In clinical practice, unexplained hypercobalaminaemia should prompt investigation for underlying disease, particularly in patients without obvious supplementation history
This is because hydroxocobalamin stays in the body for longer
Vitamin B12 (cobalamin) is a vital nutrient that plays a crucial role in maintaining healthy nerves, red blood cell production, DNA synthesis, and even the health and vibrancy of your skin
BOMSS guidance further specifies monitoring responsibilities: specialist multidisciplinary team (MDT) follow-up is recommended for at least two years after surgery, with lifelong monitoring thereafter, typically in primary care