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It occurs when genetically sensitive follicles gradually become smaller and produce finer, shorter strands

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Biotinidase Deficiency Profound biotinidase deficiency is an autosomal recessive disorder that is characterized by mutations in the BTD gene that result in enzyme activity that is less than 10% of the normal

In addition, smoking lowers the amount of oxygenated blood that reaches your face, and it can cause dry skin, uneven skin pigmentation, and deeper facial wrinkles