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While no research yet shows a connection to Hashimotos, I wanted to make note that in some cases, individuals may have normal blood levels of folate, but the folate may not be getting to the brain due to autoimmune folate receptor antibodies (FRAs), which block the transport of folate into the cerebral spinal fluid (CSF)

Considering the possibility of intervening factors from the environment, we decided to study the siblings of children with Down syndrome as a control group

[DOI] [PubMed] [Google Scholar] 50.Kadima W., Rabenstein D.L