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MATSUO (Sumitomo Chemical Co., Ltd), with the assistance of the staff of the NATIONAL INSTITUTE OF HYGIENIC SCIENCES, Tokyo, Japan and DR I
The results showed that maternal RPM supplementation in late gestation promoted more significant global DNA methylation in the offsprings liver, accompanied by a general alteration in the hepatic transcriptome, proteome, and metabolome, favoring the enrichment in glucose and lipid metabolism, glutathione, and immune system pathways (Palombo et al., 2021)
Besides their neuronal/plasma membrane location, it has been observed that a significant fraction of TRP channels is also present in organelles membranes which may be translocated as required by cells exposed to injury/inflammation (Mickle et al., 2016)
Activated JNK contributes to the dysfunction of the electron transport chain and increased ROS
Yu Y, Xie Y, Cao L, Yang L, Yang M, Lotze MT et al
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