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Metabolic reprogramming induced by glutamine metabolism Unsurprisingly, glutamine metabolism plays a critical role in tumor progression since it not only supports mitochondrial oxidative phosphorylation but also supplies metabolic intermediates for the TCA cycle, glutathione synthesis, and NEAA synthesis and simultaneously produces NADPH 157,158,159

They regulate key biological processes such as inflammation, cellular migration, proliferation, and angiogenesis [19, 20]

- Liposome formulation technology is applied to stabilize glutathione and increase bioavailability