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It also supports nerve regeneration and reduces oxidative stress two mechanisms thought to underlie its benefits for diabetic neuropathy.48 Randomized trials have shown that taking 1,0002,000mg of ALCAR daily may help reduce pain, improve vibration perception, and enhance nerve conduction in people with diabetic neuropathy especially when treatment begins early.49 Vibration perception refers to the ability to sense low-frequency vibrations, such as those from tuning forks a key part of nerve function often tested in clinical exams to assess sensory loss in the feet and legs

doi: 10.1055/s-2006-962056 55

Glutathione S-transferase pi mediates MPTP-induced c-Jun N-terminal kinase activation in the nigrostriatal pathway

It helps reduce the appearance of dark spots and uneven skin tone by inhibiting free radical activity and improving skin clarity over time

[DOI] [PubMed] [Google Scholar] Dalton TP, Dieter MZ, Yang Y, Shertzer HG, Nebert DW