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The active sites are solvent exposed and open for possible interactions with a protein, substrate or cofactor that remain to be elucidated to understand the catalytic mechanism of BshC (Vanduinen et al., 2015)

Genomics 18 (3), 680686

Depending on which muscle group is affected first, its symptoms vary from person to person and can include: tingling in the fingers or toes cramping in the arms or legs trouble with tongue and facial movements, including chewing and swallowing

Subsequently, numerous studies have emerged linking UA to neurodegenerative diseases (see Table 1)

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