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One study showed that AMs from bronchoalveolar lavage fluid (BALF) of smokers and e-cigarette users are phenotypically distinct, with macrophages from e-cigarette vapers having elevated inducible nitric oxide synthase (marker for M1 macrophages) expression and reduced CD301a (marker for M2 macrophages) expression compared with nonsmokers or smokers(29)

[DOI] [PubMed] [Google Scholar] (21).Assunta M, and Chapman S (2008) The lightest market in the world: Light and mild cigarettes in Japan

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