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Ideal for all skin types, this product is gentle enough for sensitive skin while being robust enough to tackle stubborn pigmentation issues

In some embodiments, the formulations or compositions described herein have a pH and osmolarity as described herein, and have a concentration of active pharmaceutical ingredient between about 0.01-about 20%, between about 0.01-about 10%, between about 0.01-about 7%, between about 0.01-5%, between about 0.01-about 3%, between about 0.01-about 2% of the active ingredient by weight of the formulation or composition

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When patients have a history of mold exposure, water-damaged buildings, or chemical sensitivity alongside autoimmune or psychiatric diagnoses, mast cell activation and barrier dysfunction are likely contributors