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In the case of IL-4, downstream signaling leads to the activation of the peroxisome proliferator-activated receptor gamma (PPAR) transcription factor (Guo et al., 2022)

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Highlighting glycines role in sleep regulation, non-ketotic hyperglycinemia is a rare metabolic disorder characterized by excessive levels of glycine in the blood, with sleepiness as a main symptom (Ning et al