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Establishment of the TXNIP-overexpressing diabetic animal model C57BL/6, male mice were used in healthy mouse experiments or were rendered diabetic by multiple low-dose streptozotocin (STZ) injections (3 days

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Initially developed for obesity treatment, AOD9604 showed weight-reducing effects in rodent models comparable to those of full-length GH, but without inducing diabetes or stimulating IGF-1 production