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Additionally, two-year safety data from the STEP 5 trial shows that while gastrointestinal events occurred in 82% of participants at some point during the study, most of these events were concentrated in the initial 6 months, with frequency and severity declining markedly in long-term treatment

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Once opened, it is normally treated as single-use because there is no preservative system to support repeated access

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Lyophilization removes water from the peptide under vacuum at low temperature, creating a dry powder that can be stored long-term without significant degradation (1)