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A major source of hepatic fat is fat mobilization from adipose tissue

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37 Another treatment is alpha-galactosidase

Neuroendocrine normalization: Studies in aged animal models document normalized anterior pituitary function and restored luteinizing hormone and follicle-stimulating hormone pulsatility following administration

In addition to the scarcity of human studies testing Hx replenishment as a therapeutic in SCD, another foreseeable limitation of this strategy is the cost