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Patients with a history of alcohol abuse, hepatitis or cirrhosis are at higher risk of acetaminophen toxicity, as they already have underlying liver damage. Rather than eliminating acetaminophen entirely, Lee wanted to modify its structure to reduce the harmful effects of NAPQI

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* Correspondence: Vishwanath Venketaraman, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers