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Peer review Peer review information Nature Aging thanks Maziar Divangahi for their contribution to the peer review of this work

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0.22 m) prior to use Aliquot and store reconstituted solutions at 20 C or below to minimise degradation Avoid repeated freezethaw cycles Precautions & Notes Experimental behaviour of BPC-157 is dependent on concentration, model system, and exposure conditions Due to reported interaction with multiple signalling pathways, appropriate experimental controls are recommended Prolonged exposure to light, elevated temperature, or aqueous environments may reduce stability As of 2022, BPC-157 (PL-14736) is listed by the World Anti-Doping Agency (WADA) under the S0 category of prohibited substances