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The largest gap for males in 2012 was observed in Virginia, where there was a 23.6 percentage point gap in cigarette smoking prevalence for men between Sussex County (33.5% [28.6%-38.7%]) and Falls Church City (9.9% [8.1%-12.0%])

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Nicotine may cause patients to feel less stressed right after use due to its effects on the brain but will lead to overall worsening stress levels due to nicotine withdrawal symptoms, including anxiousness

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