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According to Sharon (2013), the variations seen in many of these harmful processes and the resultant clinical illness brought on by these heavy metals are often due to variations in their absorption, distribution or metabolism rather than because of variations in their toxic mechanisms

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Ferulic acid (FA), the main active component isolated from Angelica sinensis , has been documented to increase the levels of GSH and the expression of GPX in the myocardium by upregulating AMPK2 and activating Nrf2 signaling [41, 165]

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