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Mitochondrial impairments in aetiopathology of multifactorial diseases: common origin but individual outcomes in context of 3P medicine

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In contrast, tissue-specific stem cells, found in various adult organs, are multipotent and are responsible for replenishing specific cell types

In response to mechanical stimulation of the cells or on inhibition of the Hippo pathway, YAP and TAZ translocate to the nucleus, where they can regulate gene expression through their binding to transcription factors of the TEAD family

doi: 10.1177/14791641211047135 88