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which can be enzymatically reduced back to GSH via NADPH-dependent glutathione reductase (GSR) activity [11]

We found that structurally similar ions scissored at one or two points (Supplementary Fig

Abstract Glutathione (GSH) is the main non-protein thiol in cells whose functions are dependent on the redox-active thiol of its cysteine moiety that serves as a cofactor for a number of antioxidant and detoxifying enzymes

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More recently, several studies suggested that pyroptosis is the type of cell death after APAP overdose (Wang et al., 2021