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88 On the other hand, ubiquitin ligases themselves undergo Kla

The binding of the RGD motifs to the V integrins expressed in tumor endothelial cells induces the protease-mediated cleavage of the iRGD peptide, producing two peptides, namely, CRGDR/K and GPDC

Heidari, N., Sajedi, F., Mohammadi, Y., Mirjalili, M., & Mehrpooya, M

Selective killing of cancer cells by a small molecule targeting the stress response to ROS

Preliminary Results from a Phase Ib Study Evaluating BCL-2 Inhibitor Venetoclax in Combination with MEK Inhibitor Cobimetinib or MDM2 Inhibitor Idasanutlin in Patients with Relapsed or Refractory (R/R) AML