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Side effects, such as brief soreness at the injection site, are usually mild

The once widely accepted primary role for -amyloid in sporadic AD (known as the amyloid cascade hypothesis) is currently criticised as not being the sole cause of AD, but nevertheless, amyloid accumulation is clearly a part of AD pathology and evokes multifaceted glial responses

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Blockade of interleukin-6 signalling with siltuximab enhances melphalan cytotoxicity in preclinical models of multiple myeloma

Expression of the SLC23A1 gene (SVCT1) is predominantly in intestinal epithelial cells and renal tubular cells where the transporter is found in the apical plasma membrane